Chronic migraine becomes “refractory” when preventive treatments don’t work to reduce the frequency of episodes. Treatment may include complementary therapies like neuromodulation. Migraine can often ...

The refractory period occurs right after you reach your sexual climax. It refers to the time between an orgasm and when you feel ready to be sexually aroused again. It’s also called the “resolution” ...

The refractory period refers to the time after having an orgasm during which a person is not sexually responsive. It can last from a few minutes to more than a day. Strategies to improve ...

Multiple myeloma is considered to be relapsed if symptoms of the disease appear after a time of improvement. It’s considered to be refractory when it gets worse even though it’s being treated. To ...

In a phase 1 trial, axicabtagene ciloleucel (axi-cel), an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy, showed efficacy in patients with refractory large B-cell lymphoma after ...

Hypoglycemia is the term for low levels of sugar in the blood. Refractory hypoglycemia occurs when hypoglycemia lasts for a prolonged period of time, such as a few hours to a few days. Refractory ...

Despite advances in defibrillation technology, shock-refractory ventricular fibrillation remains common during out-of-hospital cardiac arrest. Double sequential external defibrillation (DSED; rapid ...