Adherens junctions (AJs) meet the dual challenge of maintaining tissue architecture and facilitating cell movement during tissue development and renewal. Across animal species, classic cadherins ...

Researchers report the first evidence in living organisms that adherens junctions, the 'glue' between cells, actively respond to mechanical cues by remodeling their position and intensity, which in ...

The homeostasis of adherens junctions was studied using E-cadherin and its two mutants tagged by the photoconvertible protein Dendra2 in epithelial A-431 cells and in CHO cells lacking endogenous ...

Epithelial cells are joined by adherens junctions, which consist of homotypic interactions between extracellular domains of E-cadherins. Inside the cell, the tails of E-cadherins bind actin cables ...

Northwestern Medicine investigators have uncovered new insights into how intercellular "glue" functions to enable interactions between cells, as detailed in a study published in Nature Communications.