As people grow older, their immune systems do not simply slow down, they often become locked into a simmering, ...

Scientists are no longer just cataloging the damage that comes with age, they are starting to rewire the machinery inside ...

The population across developed countries is getting older and the associated frailty and debilitation are becoming major health problems. This gradual muscle loss is accelerated by the poor capacity ...

For decades, scientists have understood that aging begins at the cellular level. But one major question has remained unanswered: how does the aging of individual cells lead to the aging of entire ...

Northwestern Medicine scientists have discovered how molecular "traffic controllers" in cells influence aging and cellular senescence—a state where cells stop dividing but remain metabolically active.

Researchers found that the body’s natural recycling system, the lysosome, plays a vital role in removing the protein that drives premature aging. When this system breaks down, aging speeds up. By ...

As the brain ages, cells in the central nervous system experience metabolic dysfunction and increased oxidative damage. These cellular issues impair the ability to maintain the myelin sheath (the ...

New research reveals that aging immune cells can become locked in a self-sustaining inflammatory state, worsening the body’s ...

A small tweak to mitochondrial energy production led to big gains in health and longevity. Mice engineered to boost a protein that helps mitochondria work more efficiently lived longer and showed ...