CRISPR-Cas systems help to protect bacteria from viruses. Several different types of CRISPR-Cas defense systems are found in bacteria, which differ in their composition and functions. Among them, the ...

With the first medical therapy approved and systems like CRISPR-Cas showing up in complex cells, there’s a lot happening in the genome editing field. By Amber Dance/Knowable Magazine Published Jan 26, ...

Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins are core components of fast-evolving therapeutic gene editing tools. Scientists have used CRISPR ...

In a study published in MedComm—Biomaterials and Applications Professor Changyang Gong and his Ph.D. student Shiyao Zhou elaborate on the mechanism of CRISPR/Cas9 system. The CRISPR/Cas9 system ...

Antibiotics usually save lives—but against some bacteria, they can make things worse. That’s the case with the Shiga toxin–producing Escherichia coli, where bacterial death releases a flood of a ...

Researchers have discovered a handful of new CRISPR-Cas systems that could add to the capabilities of the already transformational gene editing and DNA manipulation toolbox. Of the new recruits, one ...

Out of the many challenges scientists face in bringing genomic medicine to patients, delivery is near the top of the list. Due to these barriers in getting the genetic payload to the correct target ...

Gene editing in plants remains challenging, with the traditional non-homologous end-joining (cNHEJ) repair pathway often hindering precision. In this study, researchers advanced CRISPR-Cas-based gene ...

A DNA-guided CRISPR platform could make RNA detection and control more stable, scalable, and precise, opening new routes for diagnostics, transcriptome engineering, and future therapeutic research.

Across all domains of life, immune defenses thwart invading viruses by making it impossible for the viruses to replicate. Most known CRISPR systems target invading pathogens’ DNA and chop it up to ...