Medscape

Alzheimer's CSF Test: Useful or Useless?

Alzheimer's Disease Cerebrospinal Fluid Test -- Useful or Useless? According to a recent editorial, neurologists should be sharpening their lumbar puncture needles in order to obtain cerebrospinal ...
Nature

Leptomeningeal metastasis from solid tumors: clinical features and its diagnostic implication

Leptomeningeal metastasis (LM), a lethal complication of malignant tumors, refers to involvement of the cerebrospinal fluid (CSF) and leptomeninges by tumor cells. Nowadays, it is considered the third ...
Medscape

Chronic Rhinorrhoea in a Woman Leads to CSF Leak Diagnosis

A 74-year-old woman was admitted to the hospital with headache, fever, intermittent right-sided otorrhoea, and rhinorrhoea. Analysis of nasal discharge confirmed the presence of beta-2-transferrin. CT ...
Nature

A noninvasive test for human prion disease using hair roots and scalp

Invasive tests like cerebrospinal fluid (CSF) examination are highly effective for diagnosing human prion disease (HPD). Real-time quaking-induced conversion (RT-QuIC) CSF assay demonstrates 80–90% ...

Belay Announces Update to NCCN Guidelines to Recommend CSF-based Genomic Profiling in Biopsy Infeasible High-Grade Gliomas

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) regarding characterization and treatment of central ...
Case Western Reserve University

Cerebrospinal Fluid Protocol

Diagnostic testing of CSF for surrogate disease markers (i.e., 14-3-3 and total tau) assumes that the patient had a history of acute dementia but did not have several conditions that might compromise ...