Researchers suggest targeting ECM-mediated regulation of autophagy levels could be used to sensitize pancreatic cancer to FDA-approved therapies.
Researchers show how damaged tissue is reshaped to trigger painful bone formation in muscles and tendons CHINA, ...
A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a ...
A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows. The ability of these cancer cells to adapt quickly and ...
A recent article in Small highlights a new method for studying tumor cell interactions and testing anti-metastatic drugs through the development of an Under-oil Open Microfluidic System (UOMS). This ...
CAFs Impact ECM and tumor growth: CAFs secrete MMPs to degrade ECM, releasing growth factors for cancer cells. ECM changes counteract CAFs and tumor cells: (a) Hard ECM triggers Twist release from ...
In a recent study published in Nature, researchers reveal a novel mechanism by which hypothalamic inflammation drives fibrotic remodeling in perineuronal nets (PNNs), a specialized extracellular ...