Researchers suggest targeting ECM-mediated regulation of autophagy levels could be used to sensitize pancreatic cancer to FDA-approved therapies.

Researchers show how damaged tissue is reshaped to trigger painful bone formation in muscles and tendons CHINA, ...

A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a ...

A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows. The ability of these cancer cells to adapt quickly and ...

A recent article in Small highlights a new method for studying tumor cell interactions and testing anti-metastatic drugs through the development of an Under-oil Open Microfluidic System (UOMS). This ...

Sarcopenia—reduced muscle mass, strength, and function—is often associated with aging and frequently impacts quality of life in the elderly. Individuals with sarcopenia are also prone to further ...

CAFs Impact ECM and tumor growth: CAFs secrete MMPs to degrade ECM, releasing growth factors for cancer cells. ECM changes counteract CAFs and tumor cells: (a) Hard ECM triggers Twist release from ...

In a recent study published in Nature, researchers reveal a novel mechanism by which hypothalamic inflammation drives fibrotic remodeling in perineuronal nets (PNNs), a specialized extracellular ...