How Louisville football performs against Eastern Kentucky is as important as how it competes against Clemson. CL Brown explains in his latest column.

Oddsmakers and bettors reveal their early prediction for LSU vs. Clemson in this Week 1 college football game.

Clemson is a 4-point favorite against LSU, according to the VegasInsider.com consensus betting line. That’s an uptick from the game’s opening point spread (Clemson -2.5). A few sportsbooks, including FanDuel, have Clemson as a 4.5-point favorite.