A number of recent trials have explored potential strategies for using immunotherapy in chronic lymphocytic leukemia (CLL). The authors explained that while molecularly targeted therapies like Bruton ...

A schematic overview illustrating how the immune microenvironment is involved in diseases across various systems, including respiratory, cardiovascular, and digestive systems. Targeting cellular ...

Now a Ludwig Cancer Research study has identified in the microenvironment of bone tumors a key architect of that resistance. Researchers co-led by Taha Merghoub and Tao Shi of the Ludwig Collaborative ...

The tumor microenvironment (TME) consists of mediators surrounding a tumor, including diverse cell types, blood vessels, and ...

The tumor microenvironment is a battleground where infiltrating immune cells either subdue or promote a cancer, all while cancer cells try to dampen the body’s defenses. 1,2 Scientists have studied ...

Inflammation covertly rewires the bone marrow, enabling mutated stem cells to rise and setting the stage for future blood disease.

Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not well understood. In a new study published in Cell Genomics, researchers at ...

When we think of type 2 diabetes, images of heart problems or kidney damage often come to mind. But lurking quietly behind these well-known complications is another serious threat—bone disease.