RNA’s Surprising Role in DNA Repair New insights could lead to improved treatments for cancer and other diseases. Francesca Storici and her research team discovered a surprising role for RNA in DNA ...

DNA and RNA methylation, initially thought to operate as distinct pathways, have been shown to interact closely, shifting our understanding of gene regulation. A team of researchers from the ...

Francesca Storici consults at Tessera Therapeutics. She has received funding from the National Institutes of Health and the National Science Foundation. Your DNA is continually damaged by sources both ...

We’re celebrating 180 years of Scientific American. Explore our legacy of discovery and look ahead to the future. In 1957, just four years after Francis Crick and other scientists solved the riddle of ...

A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...

A strand of RNA just 45 nucleotides long has been discovered to perform two key reactions required for self-replication. The ...

A giant impact on the early Earth could have brought the building blocks of RNA to our planet, which new research suggests could have quickly formed in the presence of compounds called borates. When ...

This image illustrates the chemical structure of a purine molecule, highlighting the numbering of the carbon and nitrogen atoms. The purine structure consists of a pyrimidine ring (positions 1 to 6) ...