Cells continually encounter endogenous and exogenous lesions that threaten genomic integrity. Among the principal pathways that safeguard DNA are nucleotide excision repair, mismatch repair and base ...
A review describing how glioma stem cells exploit DNA damage response plasticity through checkpoint signaling, DNA repair, epigenetic regulation, translation, metabolism, and transcriptional recovery ...
A protein tied to ALS and dementia may have a much bigger role in disease than scientists realized. Researchers found that TDP43 controls a key DNA repair process, but when the protein becomes ...
A new study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and ...
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