The NMR and Drug Metabolism Core has developed rapid and efficient approaches to investigate metabolism, metabolic stability, pharmacokinetics (PK), and chemical structure identification of small ...

The application of pharmacogenetics in identifying single nucleotide polymorphisms (SNPs) in DNA sequences that cause clinically significant alterations in drug-metabolizing enzyme activities is ...

Metabolism and individuality in drug response The need to understand individuality in drug response and associated benefits is a primary force behind the current industry trend toward the ...

The NMR and Drug Metabolism Core at Baylor College of Medicine offers tools to support the discovery, synthesis, screening, optimization, metabolism and pharmacokinetics of small molecule ligands or ...

Even well-known drugs can cause entirely unpredictable effects on metabolism, Swiss researchers have shown. Rapidly mapping ...

Next-generation obesity drugs will work differently from Ozempic and Wegovy — aiming to deliver greater weight loss with ...

Weight-loss medication has taken the world by storm and helped many overweight people. But for some, significant weight loss ...

A high-resolution spatial map of the human hypothalamus makes it possible to identify specific cells, determine their exact ...

Despite such growth, there remains a set of complex hurdles associated with drug development for rare metabolic diseases. Inborn Errors of Metabolism Drug Development 2020 is dedicated to ...