From the earliest studies with epithelial cells implanted into detrusor muscle to later experiments on smooth muscle in defined collagen gels, cell niche and extracellular matrix (ECM) have been ...

Different tissues have unique and specialized extracellular matrix (ECM) components and organization, which enables each ECM to carry out tissue-specific roles, including structural support, the ...

Scientists have found an essential factor from the extracellular matrix that regulates functionality of the breast tissue for instance during pregnancy. Scientists at the University of Helsinki have ...

In most tissues, cells are surrounded by an extracellular matrix (ECM) containing proteins such as collagen, laminin, and fibronectin. The ECM plays an important role in regulating cell function. ECM ...

Osteoarthritis (OA) is the most prevalent musculoskeletal disease that afflicts millions of people worldwide. It is characterized by the irreversible breakdown of the extracellular matrix (ECM) of ...

Tokyo, Japan – Recreating native physiological processes in manmade materials imitating the biological structures involved in wound healing has proved to be a lasting challenge. The main problems are ...