The endothelial glycocalyx integrates mechanical signals with vascular biology, playing a vital role in health and disease, particularly in sepsis and diabetes.

With a new $11.3 million Program Project grant from the National Institutes of Health, experts from the Vascular Biology Center at the Medical College of Georgia at Augusta University are working to ...

Sepsis is a life-threatening condition that often leads to ARDS, characterized by widespread inflammation and vascular injury. This study identifies lactate-driven lysine lactylation (Kla) as a ...

Sepsis, a life-threatening systemic inflammatory response triggered by infection, has long challenged clinicians with its persistently high mortality (up to 40-50% in septic shock). At the heart of ...