Epigenetic regulation has emerged as a crucial factor in tumour biology, fundamentally influencing gene expression without altering the underlying DNA sequence. Aberrant epigenetic modifications – ...

Latent EBV genomes undergo epigenetic modifications that determine the host cell-dependent activity of EBV latency promoters and may prevent productive viral replication. The epigenotype of cells in ...

Epigenetic regulation in plants encompasses a range of molecular modifications that alter gene expression without changing the underlying DNA sequence. Central to this regulation are DNA methylation ...

Understanding how cells become fat cells is a crucial part of tackling conditions like obesity and type 2 diabetes – and a ...

The process of “epigenetic memory” in nerve cells plays a key role in learning ability, memory function, and healthy brain development. Prof. Tomohisa Toda at the Max-Planck-Zentrum für Physik und ...

T cells are central mediators of autoimmune disease pathogenesis, yet their functional states are not defined solely by antigen recognition or canonical ...

Metabolic diseases such as obesity, fatty liver, and insulin resistance are rapidly increasing worldwide, but fundamental ...

Working model of the BrHDA6-BrSOT12 module in downy mildew resistance of B. rapa.

Using cannabis may cause changes in the human body's epigenome, a study of over 1,000 adults suggests. The epigenome functions like a set of switches, activating or deactivating genes to change how ...

Using single-cell epigenomic profiling of immune cells from 110 individuals, researchers show that genetic variation and ...

Sangamo Therapeutics, Inc. (Nasdaq: SGMO), a genomic medicine company, today announced it has entered into a license agreement with Genentech, a member of the Roche Group, to develop intravenously ...

This is a preview. Log in through your library . Abstract In this study, we investigated the regulatory function of miR396 in the phase transition in Arabidopsis thaliana. Using AtMIR396a/b knockout ...