Cancer researchers have long treated genetic chaos and epigenetic rewiring as separate engines of disease, two parallel ...

The role of epigenetic mechanisms in cancer has gained interest in recent studies. The reversible nature of epigenetic changes on genomic DNA and histones holds promise for the development of ...

Six epigenetic features define the new Epigenetic Hallmarks of Cancer, an add-on to the widely accepted Hallmarks of Cancer. Scientists concluded that malignant transformation requires some degree of ...

A pair of medications that make malignant cells act as if they have a virus could hold new promise for treating colorectal cancers and other solid tumors, reports a new study. The preclinical research ...

Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic "marks" in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells may ...

DNA mutations in oncogenes and tumor suppressor genes drive tumorigenesis, but epigenetic modifications, such as DNA methylation, take center stage in a new era of cancer research. 1 In a study ...

Francesco Crea is currently funded by a Prostate Cancer UK grant to develop epigenetic cancer therapies. He has also received research funding from Belgian Volition to test cancer biomarkers. Though ...

Investigators from the UCLA Health Jonsson Comprehensive Cancer Center developed an artificial intelligence (AI) model, based on tumor-associated epigenetic factors, which they say can predict patient ...

Research Areas: Cancer Pathobiology & Immunology, Cancer Genomics, Metabolomics, & Epigenetics, Carcinogenesis & Tumor Microenvironment, Metastasis & Experimental Therapeutics, Cancer Cell Biology & ...

Epigenetics is an emerging field of scientific research exploring the study of gene expression changes that occur without alterations to the DNA sequence itself. Image Credit: Juan ...

The role of epigenetic mechanisms, such as DNA or RNA methylation, histone modifications, nucleosome changes, and non-coding RNAs in cancer has gained increasing interest in recent studies. The ...

A new preclinical study by Van Andel Institute Professor Dr. Scott Rothbart and colleagues reveals how two epigenetic cancer medications approved for separate uses may hold promise for treating ...