To neuroscientist Jason Vevea, Luke Lavis is not just a chemist. He’s a modern-day magician. For the past decade, Lavis, a senior group leader and head of Janelia’s molecular tools and imaging ...

Fluorescence imaging can be conducted with long Stokes shift dyes that minimize crosstalk between the excitation source and fluorescent emission to improve the signal-to-background ratio. Regardless, ...

Eric Schreiter and Luke Lavis thought they had figured it out. In 2021, the Janelia group leaders reported that they had developed a way to combine Schreiter’s engineered protein biosensors and ...

Fluorescent dyes are molecules that are widely used in fundamental research, industrial R&D and manufacturing, medicine, and other industries. To successfully implement all advantages of usage of ...

Chemists have developed a tool for noninvasive brain imaging that can help illuminate hard-to-access structures and processes. Their small-molecule dye is the first of its kind that can cross the ...

Fluorescent molecules that absorb and emit light in the near-infrared (NIR) and short-wave infrared (SWIR) regions have significant potential for various applications. These molecules can serve as ...

Fluorescence quenching is a critical process in photophysical and photochemical studies, describing the reduction in a fluorophore’s emission intensity due to interaction with a quencher. In systems ...

Fluorescent dyes are tools used throughout biotechnology and medicine that offer a unique method of detecting and quantifying the presence of a target molecule, cell, or tissue within an even more ...

When it comes to designing ultrabright solid-state fluorescent materials, bridged crystal designs might be the key to enabling monomeric emission and accessing novel crystalline systems, reveals a new ...