The phosphodiesterase-5 (PDE-5) inhibitor, sildenafil, has been reported to produce sustained pulmonary vasodilatation in patients with pulmonary hypertension (PH). Recently, vardenafil, a more potent ...

Please provide your email address to receive an email when new articles are posted on . Researchers observed significant improvement in cerebrovascular hemodynamics after LVAD implant in patients with ...

The treatment of patients with HFpEF-PH to date has focused mainly on controlling symptoms of overhydration, using sodium-glucose cotransporter 2 inhibitors (SGLT-2is), treating comorbidities, and ...

Tectonic Therapeutic reported positive Phase 1b trial results for TX45, showing improved hemodynamics in PH-HFpEF patients without serious adverse events. Despite the positive results, the company ...

Use of percutaneous ventricular assist devices (LVADs) among patients with cardiogenic shock following acute MI continues despite a lack of supporting data and evidence of an increase in adverse ...

In the United States, a sharp rise in use of percutaneous left ventricular assist devices (LVADs) to provide hemodynamic support in recent years was paralleled by a decline in use of intra-aortic ...

Levosimendan appeared to increase in-hospital survival rates, although no long-term survival benefit was reported, among patients with comorbid heart failure and connective tissue disease–associated ...