Maintenance therapy with subcutaneous infliximab was more effective than placebo regardless of disease location or segment ...

Patients with cystic fibrosis (CF) have abnormal concentrations and composition of electrolytes and macromolecules in gastrointestinal secretions. Such alterations could change intestinal surface ...

PALI-2108 is the first and only PDE4 inhibitor in development targetingthe terminal ileum and colon for treatment of ulcerative colitis (UC) and ...

A part of the gastrointestinal tract, the small intestine (also called the small bowel) connects to the stomach and continues on to connect to the large intestine. It is made up of three main parts, ...

Inflammation from Crohn’s disease can cause thickening or scar tissue inside your small intestine, which sometimes leads to narrow areas called strictures. A strictureplasty for Crohn’s disease is a ...

Carlsbad, CA, May 27, 2025 (GLOBE NEWSWIRE) -- Palisade Bio, Inc. (PALI) (“Palisade”, “Palisade Bio”, or the “Company”), a clinical-stage biopharmaceutical company focused on developing and advancing ...

THE small intestine comprises the longest portion of the alimentary canal and yet receives small consideration in the diagnosis of intestinal tumors. The reason is the rarity of neoplasms in the small ...

This story is part of a series exploring human anatomy and physiology complexities. Each story in this collection showcases discoveries reshaping our understanding of the body's inner workings, ...

Researchers have found that immunoglobulin A (IgA) deficiency leads to disruption of the ileal gut microbiota and increased inflammation in the ileum in mice. This suggests that IgA plays an important ...

Knocking out a single gene reprograms part of the large intestine to function like the nutrient-absorbing small intestine. In a preclinical study, Weill Cornell Medicine investigators showed that the ...