The hierarchical structure of the intervertebral disc (approximately 45–55 mm diameter in the human lumbar spine and 2.5–5 mm in the rat coccygeal spine) is composed of the outer fiber-reinforced ...

Targeting senescent cells with dasatinib–quercetin preserves disc structure and modulates degeneration-associated ...

A recent meta-analysis found the breakthrough in spinal surgery revealing that augmenting minimally invasive procedures with regenerative growth factors can significantly improve postoperative ...

Intervertebral disc (IVD) degeneration and associated back pain place a significant burden on the population. IVD degeneration is a progressive cascade of cellular, compositional and structural ...

The lumbar vertebrae are the largest movable bones of the backbone. Their large size and bone strength is necessary because these vertebrae support more weight than the upper two segments of the ...

A slipped disk can happen anywhere along the spine. Despite the name, the intervertebral disk does not slip out of place. Instead, the inner material protrudes through the disk’s outer ring, causing ...