Imaging studies that use rodents sometimes involve intraperitoneal administration of pharmacological compounds. To facilitate such studies, the authors developed a simple and easily mastered technique ...
Drug delivery systems can alter drug clearance from the peritoneal cavity and drug toxicity profiles. For example, IP injection of cisplatin-loaded polymeric microspheres (100–200 µm, which releases ...
When cellulose acetate disks are placed in the peritoneal cavity of mice they become coated with cells, primarily macrophages (CAM). Colonies of granulocytes (peroxidase-positive cells) are produced ...
In peritoneal cancer, cancer cells grow within the serous membrane, a component of the peritoneal cavity. There are two main types of peritoneal cancer: primary and secondary. Primary peritoneal ...
Intraperitoneal chemotherapy is a treatment for cancers in the abdomen or belly area. This treatment delivers anti-cancer drugs directly into the peritoneal cavity, the area in the belly that contains ...
Based on the aforementioned PK/PD considerations, we elected a particle size of 4–6 µm to retard the lymphatic clearance and to promote distribution within the peritoneal cavity. TPMs have several ...
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