What are the ionization techniques for mass spectrometry? Mass spectrometry (MS) plays a vital role in many aspects of our lives, from diagnosing illness and detecting food contaminants to fighting ...

This detailed overview explains the technical mechanisms of LC-MS proteomics, including peptide separation, ion generation, ...

Electron ionization (EI) is a hard ionization method that is typically used with gas chromatography-mass spectrometry (GC-MS). The mass spectral fragmentation patterns generated by EI are used for ...

The ionization method for determination of the energy deposited in sensitive sites of irradiated objects is usually used with the assumption that deposited energy is directly proportional to the ...

With mass spectrometry imaging, chemists can create maps of the locations of biological molecules within tissues and cells. Unfortunately, the dominant imaging methods that exist today often require ...

To achieve the best results, using the right ionization method is essential. There are three main atmospheric pressure ionization (API) techniques that differ in their application concerning compound ...

α-Cleavage – The homolytic fragmentation is induced by a radical cation located at a hetero atom. Functional groups can be arranged by their ability to induce α-Cleavages. Allyl cleavage – Homolytic ...

Current drug discovery workflows rely on the synthesis and bioactivity assessment of large compound libraries, both processes which heavily depend on high-throughput (HT) experimentation to be able to ...