Ketamine, a decades-old anesthetic drug, holds much promise as a new antidepressant. It acts more quickly than traditional antidepressants—on the order of hours rather than weeks—and helps people for ...
These images demonstrate the different binding sites in NMDA receptors that the UB team has discovered are responsible for ketamine’s distinct clinical effects, as an anesthetic at high doses and as ...
Ketamine—the anesthetic co-opted as a party drug—appears to ease the symptoms of depression because it taps into the brain's opioid system, according to a small study. In recent years, evidence ...
University at Buffalo neuroscientists have identified the binding site of low-dose ketamine, providing critical insight into how the medication, often described as a wonder drug, alleviates symptoms ...
A spectrogram of brain rhythm frequencies over time predicted by the team's model. After a first, moderate dose of ketamine gamma brain rhythm power (warmer colors) emerges. Then as the dose increases ...
Despite growing off-label use, ketamine and related NMDA blockers show no reliable evidence of easing chronic pain, highlighting the urgent need for safer and more effective treatments. Review: ...
Ketamine has gotten a bad reputation as an opioid—when there's plenty of evidence suggesting it isn't one, say Johns Hopkins experts. They believe this misconception may prevent patients from getting ...
Anaesthetic-turned-recreational drug ketamine has become the subject of intense research in recent years, as scientists hunt for new and improved treatments for depression. This line of investigation ...
Ketamine leads something of a double life, straddling the line between medical science and party drug. Since its invention in the early 1960s, ketamine has enjoyed a quiet existence as a veterinary ...
BUFFALO, N.Y. — University at Buffalo neuroscientists have identified the binding site of low-dose ketamine, providing critical insight into how the medication, often described as a wonder drug, ...
New research addresses a gap in understanding how ketamine's impact on individual neurons leads to pervasive and profound changes in brain network function. A World Health Organization Essential ...
BUFFALO, N.Y. — University at Buffalo neuroscientists have identified the binding site of low-dose ketamine, providing critical insight into how the medication, often described as a wonder drug, ...