The locus coeruleus is emerging as a major new area of research interest, with many important functions such as regulating our attention and sleep. Anyone with insomnia knows the impatience and ...

The locus coeruleus is a region of the brain that is instrumental in coordinating our mental processing and is the primary source of noradrenaline in the brain, which acts to regulate arousal states ...

A new study has linked signs of heightened arousal and reactivity -- a core symptom of posttraumatic stress disorder (PTSD) -- to overactivity of the locus coeruleus (LC), a brain region that mediates ...

Researchers identify the anterior cingulate cortex as a "dial" for autonomic arousal, offering new insights into Parkinson's ...

Optogenetic stimulation of the locus coeruleus noradrenergic neurons can increase wakefulness, and high-frequency stimulation decreases noradrenaline levels and produces loss of muscle tone similar to ...

Turns out, your brain isn’t just a squishy mass of pinkish-grey. Hidden deep inside is a tiny “blue spot” that plays a major role in our cognition — and a new study shows that it goes through a ...

Tsukuba, Japan—Mild exercise results in a feeling of mental clarity and enhances cognition and memory. A possible mechanism behind such effects is the activation of the arousal center in the brainstem ...

Brainstem neuron loss alongside hypothalamus damage may explain sudden muscle weakness and excessive sleepiness in narcolepsy ...

Stress is implicated in diverse psychiatric disorders including substance abuse. The locus coeruleus–norepinephrine (LC–NE) system is a major stress response system that is also a point of ...