One of the largest bottlenecks in a modern life science laboratory workflow is at the beginning of the sample-preparation stage: It is the efficient lysis, homogenization, and grinding of difficult-to ...
Cell lysis refers to the process of breaking down the cell membrane to release cellular contents, including proteins, nucleic acids, and other biomolecules. Protein extraction is the subsequent step ...
Plasmid DNA (pDNA) is a key material for producing gene therapies, mRNA and DNA vaccines. The alkaline lysis process to isolate pDNA is simple on the benchtop, but it’s challenging at industrial scale ...
New One-Step Protocol Saves Time and Delivers Greater Consistency Traditionally, protein purification from E. coli includes four phases: harvest, bacterial cell lysis, lysate clarification, and ...