Washington demonstrated its muscle with a season-opening 38-21 win over Colorado State a week ago, though the Huskies didn't quite cover the 22.5-point spread as big favorites.

The Virginia Tech Hokies (0-1) are favored by just 2.5 points against the Vanderbilt Commodores (1-0) on Saturday, September 6, 2025.

Minnesota has the 42nd-ranked offense this season (443.0 yards per game), and has been even more effective defensively, ranking 10th-best with just 151.0 yards allowed per game.