Within a cell, the nucleus is surrounded by the nuclear envelope—two layers of phospholipid membrane that prevents the nucleus mixing with other parts of the cell, thus protecting the cell's DNA from ...

A team of Yale researchers discovered how a protein called Ndc1 coordinates nuclear pore and envelope assembly after cell division, an important component of understanding how cell nuclei change in ...

A new study published in the journal Developmental Cell has revealed how a cell nucleus can repair itself when ruptured to prevent DNA spilling out into the rest of the cell. A cell's nucleus has a ...

Expansion microscopy reveals the structure of huntingtin aggregates inside the cell nucleus. Huntington’s disease is a devastating neurogenerative disorder caused by a mutation in the HTT gene that ...

Misfolded proteins are toxic to cells. They disrupt normal functions and cause some age-related human degenerative diseases, like Alzheimer’s, Parkinson’s, and Huntington’s diseases. Cells work ...

Scientists at the Utrecht University in the Netherlands say they have identified a new way in which the toxic protein aggregates associated with Huntington’s disease may damage nerve cells and cause ...