Many surgeons recommend giving up smoking, alcohol, or drugs before surgery, but researchers have found this may also ...

Studies in animal models by UF Scripps Biomedical Research scientists have identified a protein that could shed light on how people develop tolerance to pain-relieving drugs over time, a problem that ...

Researchers say an herbal treatment used in conjunction with opioids could lessen dependency and help curb the risks associated with the potent painkillers. After years of opioid addiction and ...

Physicians have frequently prescribed a class of fentanyl drugs intended for cancer patients with high opioid tolerance to patients with back pain and migraines, which puts a new population of ...

Opioids are powerful painkillers but their use is hindered because patients become tolerant to them, requiring higher and higher doses, and overdoses can cause respiratory depression and death. A ...

UF Scripps Biomedical Research scientists have a discovered a key gene that is shedding light on how people develop tolerance to pain-relievers over time, a problem that raises risk of addiction and ...

Opioids are often prescribed for pain management after surgery — but for the 19 million people in the U.S. with a history of substance abuse, that option may not be safe or desired. Until now, there ...

When you have a mild headache or muscle ache, an over-the-counter pain reliever is usually enough to make you feel better. But if your pain is more severe, your doctor might recommend something ...

The FDA has issued new rules related to the prescribing of opioid painkillers. The rules apply to transmucosal immediate-release fentanyl, or TIRF, drugs. The drugs contain fentanyl, a powerful opioid ...

Physical dependence is where your body requires opioids to prevent withdrawal. OUD involves an addiction governed by the brain’s reward center, along with problematic patterns of opioid use. It’s ...