Background. A 36-year-old, previously healthy man presented to an accident and emergency department with right-sided abdominal pain 7 days after he sustained a trauma to his right flank. He was using ...

Background A 50-year-old man with a history of hyperlipidemia and hypertension presented to an emergency department after 10 days of fevers (temperature 40 °C), headache, malaise, myalgia, poor ...

Polyarteritis nodosa is a systemic necrotizing vasculitis with a pathogenesis that is poorly understood. We identified six families with multiple cases of systemic and cutaneous polyarteritis nodosa, ...

Some people respond promptly to therapy and can taper off treatment over many months. Others require long-term treatment. The outlook for patients with polyarteritis nodosa depends on the degree of ...

Polyarteritis nodosa vasculopathy may be caused by recessive loss-of-function mutations in a single gene (CECR1) encoding adenosine deaminase 2 (ADA2), a finding with potential clinical implications, ...