Incorporating a polygenic risk score into prostate cancer screening could enhance the detection of clinically significant prostate cancer that conventional screening may miss, according to results of ...

The role of polygenic risk scores in patients with idiopathic pulmonary fibrosis (IPF) may be influenced by telomere length, ...

Over the past decade, behavioural genetics has made great advancements in predicting human behaviour using DNA. By combining millions of genetic variants into polygenic scores (PGS), researchers can ...

Please provide your email address to receive an email when new articles are posted on . A polygenic risk score that includes rare variants did not substantially improve osteoporosis or fracture risk ...

Using polygenic risk scores along with positive family histories and breast cancer-associated gene mutations improves risk stratification for breast cancer screening. Compared with a lower polygenic ...

Please provide your email address to receive an email when new articles are posted on . In a head-to-head comparison, coronary artery calcium score improved CV risk discrimination and a polygenic risk ...

Integration of polygenic scores (PGS) into clinical practice requires robust, validated mechanisms to generate these scores. A consistent message in our reports has been that to deliver PGS-based ...

Considerable progress has been made in uncovering common single nucleotide variants and developing mechanisms for genomic profiling. Using this knowledge routinely as part of clinical and public ...