Please provide your email address to receive an email when new articles are posted on . A 1-year-old female is referred for admission to the hospital for the evaluation of fever and a rash. The ...

A 27-year-old woman presented with a 2-week history of diarrhea, fever, and pustular skin rash. She had a prior diagnosis of ulcerative colitis (UC), but was on no medication for over a year. Four ...

Please provide your email address to receive an email when new articles are posted on . A 3-year-old girl came running into her house, crying loudly with pain in her right hand. Her mother noticed ...

An international consensus statement on generalized pustular psoriasis (GPP) from the International Psoriasis Council (IPC) includes the recommendation that considerations such as body surface area ...

A 54-year-old woman presented to our dermatology department with an eruption that she had experienced episodically for 20 years. Flares were characterized by pustules that appeared within flexural ...

Generalized pustular psoriasis (GPP) is a rare, life-threatening, inflammatory skin disease characterized by widespread eruption of sterile pustules. Interleukin-36 signaling is involved in the ...

A 50-year-old man presents with a 2-day history of fever, malaise, and erythematous skin with widespread pustules. He reports a history of psoriasis and is concerned about the recent development of ...

Localized pustular psoriasis is a term that refers to a limited area of small pus-filled blisters on your skin, typically on your hands or feet. It is distinct from generalized pustular psoriasis (GPP ...

Treatment with the interleukin-36 inhibitor spesolimab was associated with improved lesion clearance vs placebo after one week, but also a greater incidence of infection and systemic drug reactions.

Secondary syphilis is known to have variable clinical symptoms; in particular, symptoms can be atypical in patients with HIV infection.3 Although various oral manifestations occur in patients with ...

Arguably the best biomarker in the world for vaccine efficacy is the “take.” The take, the reaction observed after an inoculation of smallpox vaccine, is typically a small pustular lesion that occurs ...