The c-Jun/AP-1 transcription factor controls key cellular behaviours, including proliferation and apoptosis, in response to JNK and Ras/MAPK signalling. While the JNK pathway has been well ...
The proto-oncoprotein c-Jun belongs to the dimeric AP-1 family of transcription factors, which are important regulators of cellular proliferation, apoptosis and tumorigenesis 1,2,3. AP-1 activity is ...