Antigen-driven TCR signaling in the epidermis during CD8+ TRM differentiation results in a lower TGFβ requirement for persistence and increased proliferative capacity that together enhance epidermal ...

The skin acts as the body's first line of defense against external threats. However, as we age, the epidermis—the outermost layer of skin—gradually becomes thinner and loses its protective strength.

The skin has two types of adult stem cells: epidermal and hair follicle. Their jobs seem well-defined: maintaining the skin, or maintaining hair growth. But as research from Rockefeller University has ...

Senescent skin cells, often referred to as zombie cells because they have outlived their usefulness without ever quite dying, have existed in the human body as a seeming paradox, causing inflammation ...

Rockefeller scientists uncovered how hair follicle stem cells can switch from growing hair to repairing skin when nutrients run low. The key lies in serine, an amino acid that activates a stress ...

Scientists have created human eggs containing genes from adult skin cells, a step that someday could help women who are infertile or gay couples have babies with their own genes but would also raise ...