How T cells amplify signals: New study reveals key molecular switch

Signaling is fundamental to how cells sense and respond to their environment—but in immune cells, those signals must be ...

Cysteine pathways help T cells choose between multiplying and attacking tumors

A research team from the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the ...
News-Medical.Net

How the nutrient cysteine controls cancer-fighting power of T cells

A research team from the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the ...
ascopubs.org

T-cell effector cytokine signature as predictor of survival and toxicity in metastatic NSCLC patients treated with immunotherapy.

Circulating CD28-KLRG1+CD8+ T cells as prognostic indicators in advanced NSCLC chemoimmunotherapy. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not include ...
EurekAlert!

T cell-based cancer immunotherapy: Opportunities and challenges

CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...
Seeking Alpha

HCW Biologics Announces Positive Research Results for CAR-T Cell Therapy Manufactured Utilizing Its Commercial-Ready Proprietary Compound, HCW9206, Published in Science Advances

Commercialization ready compound supports a new method of generating highly functional human CAR-T cells for treating infectious diseases and cancer In experimental models, human CAR-T cells ...
Targeted Oncology

Statins May Augment Outcomes During CD19 CAR-T Therapy for R/R LBCL

Concurrent statin therapy was associated with significantly improved survival outcomes and reduced neurotoxicity in patients ...