Elongation, a crucial step in the translation process of protein synthesis, gets disrupted by amino acid sequences with an abundance of N-terminal aspartic and glutamic acid residues in eukaryotic ...

The human immunodeficiency virus (HIV), which is the cause of AIDS, is a master of deception, using just nine genes to hijack ...

HIV is a lifelong infection that, without proper antiviral treatment, will kill cells of the immune system and leave individuals susceptible to infections and cancers. The longevity of this virus ...

Understanding how HIV replicates within cells is key for developing new therapies that could help nearly 40 million people around the world who are living with HIV, the immune system virus that causes ...

In a finding that could have profound implications for AIDS vaccine design, researchers led by a team at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National ...

Researchers at the University of Iowa Carver College of Medicine and University of Nebraska Medical Center (UNMC) have created a three-dimensional picture of an important protein that is involved in ...

The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain. While symptoms can now be better managed with lifelong treatment, there is ...

The efficiency of HIV-1 replication hinges on the dynamic interplay between viral RNA and an array of viral and host proteins. At the core of this process is the dual role of the unspliced viral RNA, ...

A team of scientists at the Salk Institute and Rutgers University has determined the molecular structure of HIV Pol, a protein that plays a key role in the late stages of HIV replication, the process ...

The reason a highly effective HIV vaccine has eluded medical researchers to date is the speed with which the virus evolves. HIV, it appears, can find ways around any antigen that has been thrown at it ...

Nearly half of HIV infected patients suffer from impaired neurocognitive function. The HIV protein transactivator of transcription (Tat) is an important contributor to HIV neuropathogenesis because it ...

People living with HIV face a greater risk of developing lung diseases at a much younger age, even if they have never smoked.