Making chemical handles that latch onto amino acids is a strategy used to make covalent drugs, antibody-drug conjugates, and biochemical probes. Cysteine and lysine are common points of attachment, ...

This review synthesizes progress in pathway optimization, regulatory rewiring, and microbial cell factory design that has driven L-Trp titers to industrially relevant levels while enabling the ...

Skatole is an infamously smelly molecule that, in some anaerobic bacteria, is synthesized from ʟ-tryptophan in a four-step process. Now, researchers have found that certain aerobic bacteria only need ...