James F. Howard Jr, MD, professor of neurology at the University of North Carolina at Chapel Hill, explains how nerve and muscle signaling in the neuromuscular junction go awry in myasthenia gravis.

The neuromuscular junction (NMJ) is a specialised synapse responsible for translating neuronal signals into muscle contractions, forming the basis of voluntary movement and postural control. Integral ...

An international research team led by a University of Ottawa Faculty of Medicine investigator has revealed ultra-detailed intricacies in how nerve signals activate at the neuromuscular junction, a ...

The neuromuscular junction—where nerves and muscle fibers meet—is an essential synapse for muscle contraction and movement. Improper function of these junctions can lead to the development of ...

Frog neuromuscular junction fly-through. Shown in red is a large muscle fiber (diameter 50 micrometers) that is innervated by a myelinated axon colored in white. The interface between muscle and axon ...

The neuromuscular junction - where nerves and muscle fibers meet - is an essential synapse for muscle contraction and movement. Improper function of these junctions can lead to the development of ...

The neuromuscular junction is the synapse or junction of the axon terminal of a neuron within a muscle fiber plasma membrane. Several diseases involve the neuromuscular junction as the primary site of ...

Researchers have created a human-derived neuromuscular junction from a person with amyotrophic lateral sclerosis (ALS) with the goal of testing anti-ALS drugs that not only prevent neuronal death but ...

ORLANDO, Fla.--(BUSINESS WIRE)--Hesperos, Inc. has increased its pioneering human-on-a-chip drug testing capabilities by adding a new in vitro, human-human neuromuscular model to its patented ...

Neuromuscular diseases are caused by problems in the way muscle cells, motor neurons, and peripheral cells interact. Researchers from the Max Delbrück Center for Molecular Medicine in the Helmholtz ...

ORLANDO, Fla.--(BUSINESS WIRE)--In a recent study published in Biomaterials, a team of researchers led by Hesperos Chief Scientist Dr. J. Hickman established a significant finding to better understand ...

The flow of calcium and potassium ions keeps muscles contracting in the diaphragms of neonatal mice, but if a key protein receptor is missing, fatigue sets in more quickly. In this webinar, Evelien ...