LaBonne is president of the Society for Developmental Biology and the Erastus Otis Haven professor of molecular biosciences at Northwestern University. Imagine a world without lifesaving medicines, ...

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...

K. C. Kent Lloyd is a professor in the Department of Surgery, School of Medicine, director of the Mouse Biology Program and NAMs Testing Center and associate director of the Comprehensive Cancer ...

A social media post from the US Food and Drug Administration this week shows a big-eyed macaque staring out from behind bars. “Some drugs use 144 monkeys on average for preclinical testing,” the post ...

Every year, more than 100 million animals are used globally in biomedical research, yet over 90% of drugs that appear effective in animal trials fail during human clinical testing. 1 This staggering ...

Several in vivo swine models of benign biliary stenosis (BBS) have been recently reported for preclinical studies of novel endoscopic techniques and devices. The aim of this study was to evaluate the ...

The National Institutes of Health (NIH) announced it is embracing a new program aimed at expanding innovative, human-based science to decrease the use of animals in research. According to the NIH, ...

A recent op-ed in The Hill praising the National Institutes of Health’s new initiative to promote human-based technologies as a “major victory for animal ethics in science” oversimplifies a far more ...

For decades, scientists have relied on animal research to propel modern medicine forward, with animal testing being involved in routine vaccinations as well as cancer therapies. However, the status ...