Centrosome duplication is under precise control and occurs only once in a normal mammalian cell cycle. Disruption of this process causes centrosome amplification, unequal segregation of chromosomes ...

Angelina Jolie shows mastectomy scars to spotlight breast health on TIME France. The Oscar-winning actor appears on the first ...

BRCA1-associated ring domain 1 (BARD1) is the main binding partner of BRCA1 and is essential for the tumour-suppressor functions of BRCA1. The BARD1–BRCA1 heterodimer has ubiquitin ligase activity ...

Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of ...

The BRCA1 gene is a sequence located on the long arm of chromosome 17, at position 17q21. The gene spans around 100 kilobases and codes for a tumor suppressor protein containing 1863 amino acids. This ...

The current testing rate for BRCA 1/2 mutations is currently 68% in HER2-negative early breast cancer, but eligible patients could receive better care if tested. The current rate of BRCA1/2 testing ...

Research shows that the breast cancer gene 1 (BRCA1) not only pushes accurate DNA repair to guard against cancer but promotes subsequent activity in tumor suppression. A new study led by The ...

The full name of the BRCA1 gene is “breast cancer 1, early onset,” and it codes for a tumor suppressor protein. Tumor suppressor proteins help repair DNA that has become damaged in order to ensure the ...

Researchers report a new, previously unrecognized function of the BRCA1 gene that explains why BRCA1 gene mutation carriers are at increased risk of breast and ovarian cancer. The human body holds ...

Angelina Jolie has shared her mastectomy scars in a new photoshoot.The 50-year-old actress underwent a preventative double ...

Sometimes the most stunning advances in science are based on a hunch that a dedicated investigator just can’t shake. That was the case with Mary-Claire King, professor of genome sciences and of ...

Court rules unanimously that Myriad Genetics "did not create anything." June 13, 2013 -- The Supreme Court ruled today that isolated human genes cannot be patented, a partial defeat for Myriad ...