Immune cells in the bone marrow microenvironment of AML patients are key in distinguishing a response to immunotherapy. A team of researchers from Colombia Engineering and Irving Institute for Cancer ...
A research team made a pivotal discovery in the field of cancer immunotherapy. The team identified a specific population of immune cells that play a critical role in successful treatment of relapsed ...
Researchers identified ten ferroptosis-related lncRNAs associated with AML prognosis. These lncRNAs were used to construct a prognostic model, effectively predicting patient survival. High-risk ...
The most-read coverage of the latest updates in acute myeloid leukemia (AML) for 2025 focused on the evolution of targeted therapies, the promise of off-the-shelf chimeric antigen receptor (CAR) ...
Acute myeloid leukemia (AML) cells under the microscope, in purple. There is a serious need for finding better ways to treat AML that comes back after initial treatment. Chimeric antigen receptor (CAR ...
The tumor microenvironment (TME) consists of mediators surrounding a tumor, including diverse cell types, blood vessels, and ...
Inflammation covertly rewires the bone marrow, enabling mutated stem cells to rise and setting the stage for future blood disease.
Cell types detected in the bone marrow of a responder patient pre-treatment (left) and post-treatment (right). Contour lines mark cell groups with similar spatial neighborhoods, highlighting ...
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