Liver cancer cells thrive on fat, posing a serious risk of cancer diagnosis for millions of people living with fatty liver disease.

Liver cancer cells thrive on fat, posing a serious risk of cancer diagnosis for millions of people living with fatty liver ...

Enzymes known as kinases play a critical role in cell growth, metabolism and signaling in a multitude of organisms across the ...

Enzymes are vital to metabolism and drive countless biological processes in humans, plants, and industry. Yet, when ...

Scientists have uncovered a molecular "on–off" switch that helps lung adenocarcinoma—the most common form of lung cancer—grow ...

CYP3A4 inhibition elevates serum DHE levels, raising the risk of vasospasm leading to cerebral ischemia or ischemia of the extremities.

Herein, we have developed a drug-loaded matrix metalloproteinase (MMP)-responsive micellar nanoparticle (NP) intended for minimally invasive intravenous injection during the acute phase of myocardial ...

Cofactor mimicry represents an attractive strategy for the development of enzyme inhibitors but can lead to off-target effects due to the evolutionary conservation of binding sites across the proteome ...

"BioIVT continues to pioneer critical research, including recent findings around the evaluation of CYP- and non-CYP enzyme-based metabolism of drug candidates in drug development and drug-drug ...

The CYP17A1 inhibitors market is projected to attain USD 1,350 million by 2025, expanding at a robust CAGR of 8.5% between 2025 and 2032, supported by strong pipeline activity, expanded ...

Mergers, acquisitions, and collaborative commercialization strategies are likely to intensify as stakeholders seek to capture growth across both developed and emerging regions. The CYP17A1 inhibitors ...