Using advanced microscopy techniques and computational modeling, researchers have discovered how herpesvirus infection affects the host-cell nucleus. Researchers at the University of Jyväskylä ...

Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.

Research at the University of Jyväskylä (Finland) reveals that autonomous parvoviruses, such as canine parvovirus, are highly capable of affecting the internal balance of the nucleolus. The results ...

Home > Press release: A tale of coevolution: Nuclear speckles ...

New findings show that the genome’s 3D structure is constantly changing, with NIPBL guiding loop formation that regulates active genes. Faulty folding dynamics may underlie cancers and developmental ...

Herpes simplex virus type 1 (HSV-1) infection dramatically remodels the host cell's nuclear structures. Infection leads to ...

Over the years, cell biology has built a detailed picture of how cells compartmentalize their internal functions. Central to this organization is the nucleus, which houses the genetic material and is ...

A giant virus discovered in Japan is adding fuel to the provocative idea that viruses helped create complex life. Named ushikuvirus, it infects amoebae and shows unique traits that connect different ...

Researchers in Japan have identified a striking new way immune cells strip DNA out of dying neighbors, a process they call ...

A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...

Biomolecular condensates were long believed to be simple liquid blobs inside cells. Researchers have now uncovered that some are actually supported by fine protein filaments forming an internal ...

The story of how life began on Earth grows even more intriguing when viruses enter the picture. These microscopic particles are thought to have ...