RNA therapeutics target translation rather than DNA, aiming to correct shared protein production errors. By enabling cells to read through premature stop codons, engineered tRNAs could restore ...
UCLA researchers use lipid nanoparticles to insert full CFTR gene into airway cells, restoring function and opening new ...
Researchers engineered lipid nanoparticles to deliver a full CFTR gene into human airway cells, restoring near-normal ...
Researchers develop a single genome-editing strategy to treat multiple disorders caused by nonsense mutations, promising efficient and cost-effective therapies.
BioMed Realty, the largest private operator of real estate for the life science and technology industries, today announced the completion of the lease-up of the newest laboratory building at Babraham ...
Pharmaceutical Technology on MSN
RNA-targeting small molecules: a new frontier of drug discovery
With big pharma signalling interest in novel RNA-targeted approaches, the term “druggable” is being redefined as technology advances.
Robert Hettich conducts research in ORNL's biological mass spectrometry laboratory. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy Scientists at ...
News Medical on MSN
New gene editing approach offers hope for cystic fibrosis patients
UCLA researchers have developed a lipid nanoparticle-based gene-editing approach capable of inserting an entire healthy gene ...
Mitochondria possess their own mRNA translation system, mediated by specialized mitoribosomes. Dysregulation of mitochondrial translation disrupts metabolic homeostasis and is linked to various ...
'Inheritance through homology' is the most common and generally more accessible approach to function prediction, but orthology should be established where possible to improve confidence in predictions ...
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