For example, Ubrelvy can interact with certain drugs called strong CYP3A4 inhibitors, such as clarithromycin. Ubrelvy is taken by adults to treat certain kinds of migraine episodes. An interaction ...

Examples of ACE inhibitor drugs: Here are some ACE inhibitor ... activity of an enzyme in your body called cytochrome P450 3A4 (CYP3A4). This enzyme helps break down Rapamune.

People are only just realising that grapefruit interacts badly with certain types of medication, including birth control and ...

For example, a high blood concentration of some statins is realised when taken concurrently with clarithromycin, as the latter inhibits the CYP3A4 enzyme responsible for statin metabolism.10 This can ...

Prediction is very difficult, especially about the future”; whether it is the Nobel laureate Niels Bohr or others who have ...

In this video, Aruna Padmanabhan, MD, discusses therapy combinations for the treatment of PIK3CA-mutated metastatic breast cancer.

It is eliminated by metabolism through the CYP3A4 pathway and excreted through feces. Therefore, if patients are on a potent CYP3A4 inducer such as phenytoin or rifampin, the daily dose of ...

Using genetic markers to adjust initial doses of cyclosporine or tacrolimus may prove difficult, considering the variety of polymorphisms known to affect CYP3A4, CYP3A5, and MDR1. The current ...