Published as an arXiv preprint, the paper details how unsupervised and self-supervised AI models are matching or surpassing supervised systems while uncovering biological patterns that traditional ...
Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression. Scientists have now developed a way to silence that cellular noise, ...
Standardize tumor classification and variant annotation for reproducible cohort building with COSMIC
Accurate interpretation of cancer genomics depends on standardized disease classification, tumor characterization, and ...
A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...
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Promoters and enhancers: Tool catches gene-controlling DNA sequences doing each other's jobs
Researchers at the Weill Institute for Cell and Molecular Biology have uncovered new evidence that two major types of gene-controlling DNA sequences, promoters and enhancers, operate with a shared ...
Engineers at the University of Pennsylvania and Rice University have refined a technology for editing individual genetic ...
A mysterious RNA found in breast cancer led scientists to uncover an entire hidden class of cancer-specific RNAs across ...
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Combining gene and biomarker screening for newborn health
For more than six decades, biomarker-based newborn screening has played a pivotal role in reducing infant mortality and long-term disability by enabling early detection of metabolic and endocrine ...
This study proposes a cross-species transcriptomic framework to predict vaccine reactogenicity, with implications for preclinical vaccine safety assessment. The findings show that mouse muscle ...
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