Alternatives to opioids are desperately needed to better treat moderate to severe acute pain, but to date, we’ve seen few ...

Researchers at Scripps Research have redesigned fentanyl at the molecular level, challenging decades-old assumptions about opioid chemistry.

Researchers report that acetazolamide prevented adverse brain changes caused by cocaine withdrawal in mice, suggesting the approved drug could be repurposed to target relapse-related pathways.

Researchers find that a common glaucoma drug, acetazolamide, can reverse brain changes and prevent relapse in opioid use disorder.

As pain is such a heterogeneous indication, significant opportunities remain for a variety of different and more effective non-opioid treatment options to be developed.

Trevi Therapeutics, Inc. (Nasdaq: TRVI), a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio™ (oral nalbuphine ER) for the treatment of chronic cough in patients ...

TBS-2025 to be investigated in combination with a menin inhibitor in mutNPM1 r/r AML TAMPA, Fla., Feb. 17, 2026 /PRNewswire/ -- TuHURA Biosciences, Inc. (NASDAQ:HURA) ...

Scripps Research scientists have re-engineered fentanyl’s core structure to retain potent analgesia while limiting respiratory depression in preclinical tests – a strategy that could inform ...

Enveric Biosciences (NASDAQ: ENVB) (“Enveric” or the “Company”), a biotechnology company advancing novel neuroplastogenic small-molecule therapeutics to address psychiatric and neurological disorders, ...

Indiana mom Stacey Croston never thought she’d find herself grieving her daughter Mona after she died of fentanyl poisoning in 2020, let alone traveling 1,000 miles south every year to ...

There’s a Parks and Recreation episode where Leslie Knope tries to ban sugary drinks to save public health. She’s well-intentioned, deeply earnest, but her “solution” is completely unworkable.