Venus Williams, 45, returned to action and French 17-year-old wild card Moise Kouame made history in the first round.

Roger Federer won four Miami Open titles during his career, with the first coming against Rafael Nadal in 2005. Their meeting marked the start of what would become one of tennis’s great rivalries.

It's just the latest disappointment for Iga Swiatek, who was eliminated in the quarter-finals at the Australian Open and in the WTA 1000 events in Doha and Indian Wells.

Moise Kouame made tennis history Thursday in his Miami Open debut, becoming the youngest player since Rafael Nadal to win a Masters-level event.