In the quest for RNA biomarkers indicative of fruit maturity, a cost-effective, reliable workflow is crucial. Accurate harvest timing is critical for shelf life and apple quality, but at present, ...

In RNA-seq library preparation, selecting the appropriate number of PCR cycles is a critical balancing act to avoid overcycling.

Researchers at the Department of Chemical Engineering and Biotechnology (CEB) have found a new way to organize molecules ...

Scientists at IOCB Prague are uncovering new details of gene transcription. They have identified a previously unknown molecular mechanism by which the transcription of genetic information from ...

Researchers from the Faculty of Engineering at The University of Hong Kong (HKU) have developed two innovative deep-learning algorithms, ClairS-TO and Clair3-RNA, that significantly advance genetic ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

A total of 68,579 cells from LUAD patients revealed heterogeneous transcriptomic profiles of AT2 tumor cells and facilitated the identification of cancer cell subtypes that deviated from the normal ...

Researchers have sequenced the oldest RNA ever recovered, taken from a woolly mammoth frozen for nearly 40,000 years. The RNA reveals which genes were active in its tissues, offering a rare glimpse ...

Immunotherapy has been a revolutionary breakthrough for cancer therapeutics, but it is still hampered in that it only benefits certain patients. Moreover, the molecular determinants of immunotherapy ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...