The results of a randomized controlled trial (RCT) indicate that meningococcal B vaccine is not effective at preventing ...

Utility of the 70-Gene MammaPrint Assay for Prediction of Benefit From Extended Letrozole Therapy in the NRG Oncology/NSABP B-42 Trial Patients with advanced lung cancer reporting at least moderate ...

Contrary to existing evidence from observational studies, the meningococcal B vaccine (4CMenB) has no effect on preventing ...

A novel GLP-1 receptor agonist (RA) pill called orforglipron leads to a larger reduction in blood sugar levels after a year than the current available oral GLP-1 RA (semaglutide), finds a phase 3 ...

Researchers at The Hospital for Sick Children (SickKids), working with international collaborators and youth and family ...

‘A short-acting psychedelic intervention for major depressive disorder: a phase IIa randomized placebo-controlled trial’ by David Erritzoe et al. was published in Nature Medicine at 16:00 UK time on ...

Prospective assessment of adenocarcinoma of esophagogastric junction (AEG) following radical resection: Real-world insights from the CLAEG study. A randomized controlled phase III study comparing ...

When Elise Felicione tried to design a clinical trial for a supplement, 5 things got in the way. It’s a lesson for the ...

Objectives To evaluate the efficacy of a new multicomponent, exercise-based injury prevention programme in football players 13–19 years old. Methods Two-arm cluster-randomised controlled trial with ...

Rare disease is a major – and growing – area of clinical research and drug development. Of the FDA’s 46 novel drug approvals ...