Iranian and U.S. negotiators will resume talks on Friday in Rome to resolve a decades-long dispute over Tehran's nuclear ambitions, despite Iran's supreme leader warning that clinching a new deal might be insurmountable amid clashing red lines.

Iran and the United States are set to resume nuclear talks in Rome amid rising tensions, hard-line demands, and Israeli threats of military action. With uranium enrichment at the core of the standoff,

Iran and the United States are preparing for a fifth round of negotiations over Tehran’s rapidly advancing nuclear program, with enrichment emerging as the key issue